“Hormonal IUDs like Mirena and Jaydress can have full-body effects noticeable in breast imaging scans even though they work by releasing hormones directly into the uterus, a not-yet-published study out of Germany suggests.
The finding counters the popular understanding that IUDs work purely locally, lead author Dr. Luisa Huck of RWTH Aachen University's department of diagnostic and interventional radiology, said in a Q&A document for reporters. "Our study results suggest that this is not true."
In fact, the researchers found the IUDs' full-body hormonal effects were similar to those of hormone replacement therapy, a press release says. They say their findings show it's "plausible that IUDs can have side effects similar to that of other hormonal treatments," as women have long reported. “
“The study authors say their work is important to validate women's reports of full-body side effects from IUDs, and to help patients and clinicians make informed decisions about contraception.”

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