Comparative Effectiveness and Safety of Intrauterine Contraception and Tubal Ligation
/February 23, 2022
Journal of General internal Medicine
February 23, 2022
Journal of General internal Medicine
Read MoreWith this case, we strengthen previous observations regarding mood changes under LNG-IUS. Moreover, we illustrate that psychiatric symptoms may also occur as ADRs during the subsequent insertion. Thus, we emphasize that psychiatric symptoms have to be clearly communicated as ADRs to patients with LNG-IUS within a written informed consent and should be routinely examined by gynecologists.
Read MoreGiven the current gap in the literature and trends in LNG-IUD use in nulliparous young women, studies are needed that specifically look at the interaction of nulliparity, long-term use of LNG-IUD, and return to normal fertility. Herein, we review the available literature on the mechanism of action of IUDs with a specific focus on the effect on endometrial gene expression profile changes associated with IUDs.
https://www.springer.com/journal/11920
Read MoreRead MoreIn our current climate focused on improving access to IUDs, it is essential to address and reduce barriers to IUD removal when desired, in order to preserve reproductive autonomy.
Read MoreProgestin-only methods including the progestin-only pill (POP), levonorgestrel (LNG) IUD, etonorgestrel implant or depot medroxyprogesterone acetate (DMPA) have the potential to negatively affect mood symptoms for women with or without baseline mood disorders, including PMDD. Careful counseling and close follow-up is recommended for patients with PMDD seeking these contraceptive methods.
Read MoreReasons for discontinuation of IUD:
Bleeding Pattern (27.5%), Pain (25%), Weight Gain (5%); Other Reasons (42.5%)
Read More....The strongest data appear to be the deleterious effects of levonorgestrel-releasing IUDs on percent lean and fat body mass.
….Use of the levonorgestrel-releasing IUD, commonly used to treat abnormal bleeding in the perimenopause, increased the risk of developing breast cancer in postmenopausal women
Read MoreA 22-year-old G1P1 Caucasian female had hysteroscopic removal of a perforated intrauterine device during which the steroid reservoir of the intrauterine device was lost. Isolated steroid reservoirs are radiolucent on plain film radiography. We located the reservoir in the peritoneal cavity with magnetic resonance imaging and removed it via laparoscopy.
Read More“HC (Hormonal Contraception) use significantly increased the odds of ever being diagnosed with depression in all age groups. Women and their providers should balance the risks and benefits of initiating HC. Specifically, younger women, and be advised of the risks that HC presents in terms of a potential association with depression. Efforts to develop standardized protocols for discussing the risk-benefits for HC therapy should be pursued.”
“No other contraceptive method has undergone so rapid and thorough a change of medical reputation as that experienced by intrauterine devices over the past few years.” These words from United States-based contraceptive researcher Christopher Tietze in 1966 also characterize the last 10 years in the United States.”
Read MoreRead MoreBecause adolescents are at higher risk of sexually transmitted infections (STIs), obstetrician–gynecologists should continue to follow standard guidelines for STI screening. They should advise adolescents who choose LARC methods to use male or female condoms consistently (dual method use) to decrease the risk of STIs, including human immunodeficiency virus (HIV). Obstetrician–gynecologists should counsel all sexually active adolescents who do not seek pregnancy on the range of reversible contraceptive methods, including LARC, and should help make these contraceptives readily accessible to them.
Read MoreRecent levonorgestrel-IUD use may be associated with CIN2, a lesion with a high rate of regression, but not CIN3, which is considered a true pre-cancerous lesion. The observed association between levonorgestrel-IUDs and CIN2+ was modest but warrants further investigation. It may have clinical importance for contraceptive counseling if this finding is shown to be consistent across other studies and other populations.
Read MoreThe overall perforation rate was 2.1 per 1000 insertions for LNG-IUS users 1.6 per 1000 insertions for copper-IUD users……. LNG-IUS users had a borderline higher risk of perforation compared with copper-IUD users.
Forty-five (58%) of the 77 perforations were associated with suspected risk factors……
Breastfeeding…… and time since delivery remained significant risk factors in perforations detected after 12 months.
No perforations resulted in serious injury to intra-abdominal or pelvic structures.
Read MoreTout effet indésirable suspecté d’être lié à l’utilisation du dispositif intra-utérin Mirena peut être signalé, par les patientes ou les professionnels de santé, en tant qu’effet indésirable associé à un médicament sur https://solidarites-sante.gouv.fr/soins-et-maladies/signalement-sante-gouv-fr/ .
Recent clinical trials have identified side effects of LNG-IUD that appear to be systemically mediated, including depressed mood and emotional liability.
Read MoreRead MoreWe encourage contraceptive counseling and removal protocols that directly address historical reproductive injustices and that honor patients' wishes.
Read MoreJaydess should be used with caution after specialist advice, or removal should be considered in women with existing or new severe headache, migraine, jaundice, severe arterial disease such as stroke or myocardial infarction, or marked increase in blood pressure.